Credentials that matter
Skills and tools
- NRC Regulations
Required qualifications
- Masters in Radiochemistry, Chemistry, Chemical Engineering, Nuclear Engineering, or a closely related technical discipline. 10+ years of progressively responsible experience in radiochemistry, isotope production, radiochemical processing, nuclear chemical operations, pharmaceutical/radiopharmaceutical manufacturing, or a closely related field. with c GMP manufacturing (US and EU requirements), particularly radiopharmaceuticals, medical isotopes, APIs, radioactive starting materials, or other regulated pharmaceutical manufacturing. with CMC development, process characterization, technology transfer, process validation, continued process verification, and manufacturing science and technology (MS&T).
- Direct experience with Lu-177 production, lanthanide separations, target dissolution, radionuclide purification, or medical-isotope manufacturing.
- Demonstrated experience leading technical teams responsible for complex chemical, radiochemical, or manufacturing processes.
- Strong technical background in radiochemical separations, purification, radioactive-material handling, analytical chemistry, and process development.
- Demonstrated experience translating laboratory or development processes into reliable manufacturing operations. with process development, scale-up, process optimization, technology transfer, troubleshooting, and technical lifecycle management. working in highly regulated environments requiring disciplined procedures, documentation, configuration control, and quality systems.
- Demonstrated ability to lead complex technical investigations and make sound decisions using scientific and engineering data. developing technical procedures, specifications, reports, process documentation, and training materials.
- Strong leadership, communication, technical writing, organizational, and problem-solving skills.
- Demonstrated ability to collaborate across Manufacturing, Operations, Engineering, Quality, Regulatory, Radiation Safety, and other multidisciplinary organizations. with various regulatory regimes affecting isotope production and processing (FDA, NRC, DOE, etc.) regulatory frameworks relevant to radioactive-material and isotope manufacturing.
About this role
Oklo Isotopes is building scalable U.S. radioisotope production capabilities in facilities dedicated to producing essential isotopes for healthcare, space, industry, research, and defense applications. Oklo’s isotope operations include the production and processing of medically and industrially important radioisotopes using advanced radiochemical processes, hot cells, gloveboxes, and specialized nuclear facilities.
Responsibilities
- Lead the CMC and radiochemistry organization for isotope process development, implementation, technical support, and lifecycle management.
- Lead Lu-177 production and Am-241 and Ra-226 processing, including dissolution, separation, purification, recovery, impurity control, characterization, and waste minimization.
- Establish the technical basis for manufacturing processes, including process flows, material balances, critical parameters, operating ranges, specifications, and controls.
- Lead development, scale-up, optimization, and implementation of radiochemical processes in hot cells, gloveboxes, and laboratory or remote systems.
- Lead technology transfer and manufacturing readiness, including processes, equipment, analytics, procedures, training, and documentation.
- Establish and maintain the c GMP technical framework, including process characterization, validation, continued verification, change control, deviations, investigations, and continuous improvement.
- Own the analytical strategy for products, intermediates, impurities, waste streams, and process performance.
- Serve as the senior technical authority for process troubleshooting and optimization, focused on yield, purity, recovery, reliability, cycle time, waste, dose, and capacity.
- Support equipment design, commissioning, qualification, startup, and operational readiness with Manufacturing, Operations, Engineering, Quality, Radiation Safety, Regulatory, and Supply Chain.
- Build, mentor, and manage the radiochemistry team; establish technical standards, procedures, training, and documentation; and promote safety, quality, rigor, and operational excellence.
Preferred qualifications
- Passionate about unleashing beneficial isotopes and building domestic isotope-production capabilities.
- A strong technical leader who can maintain scientific rigor while moving programs rapidly toward manufacturing.
- Committed to nuclear safety culture, product quality, procedural compliance, and operational excellence.
- Capable of moving comfortably between detailed radiochemical problems and broader program and organizational decisions.
- Able to develop people and build a high-performing technical organization.
- Comfortable making decisions in technically complex environments where complete information may not always be available.
Location, schedule, and travel
on-site position located in Austin, Texas.
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